Hematology Oncology
Dr. Charles G. Drake is a physician-scientist with a Ph.D. in immunology, whose work focuses on understanding and fighting advanced-stage cancers with the immune system. He is known for rapidly incorporating discoveries made in the research lab into innovative clinical trials, including anti-tumor vaccines. The Drake laboratory was the first group to show that LymphocyteActivation Gene–3 (LAG-3) is a cell surface marker for CD4 cells with regulatory function (Treg) and that blockade of LAG-3 with a monoclonal antibody could restore anti-tumor immune responses by mitigating CD8 T-cell tolerance in vivo. Further work demonstrated that LAG-3 and PD-1 were co-expressed on functionally exhausted CD8 T cells, suggesting that blockade of multiple immune checkpoints might be required to restore anti-tumor immunity. These discoveries were then translated into clinical trials. His most recent work has focused on the body’s immunological response to radiation therapy and how immunotherapy and radiation therapy can be used in concert to treat cancer. His research has been published in prestigious journals such as the New England Journal of Medicine, Cancer Research, the Journal of Clinical Investigation, and the Journal of Clinical Oncology. Prior to joining NewYork-Presbyterian/Columbia, Dr. Drake served as the co-director of the Cancer Immunology Program at Johns Hopkins Kimmel Cancer Center. He is also a professor of oncology, urology, and immunology. As co-director of the Prostate Cancer Multi-Disciplinary Clinic, he developed a novel transgenic model of prostate cancer, in which a unique antigen is expressed exclusively in the prostate gland and in prostate tumors. Dr. Drake received both his bachelor’s degree in electrical engineering and his master’s degree in biomedical engineering from Rutgers University. He completed a Ph.D. program at the National Jewish Center for Immunology and Respiratory Medicine at the University of Colorado Health Sciences Center, and later earned his M.D. from the University of Colorado as part of the MSTP program. He did his internship and residency in internal medicine at the Osler Medical Service of Johns Hopkins Hospital, and did his medical oncology fellowship training in the Johns Hopkins Department of Oncology.
An oncologist is a medical professional who has the education and training necessary to diagnose and treat various type of cancers. Oncologists practice in hospitals and medical centers, university hospitals, and research organizations. In addition to diagnosing and treating tumors and cancer, they conduct research to learn more about cancer and how it acts in the body to help develop new treatment options.
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MDGender
MaleMonday:
9:00AM - 5:00PM
Tuesday:
9:00AM - 5:00PM
Wednesday:
9:00AM - 5:00PM
Thursday:
9:00AM - 5:00PM
Friday:
9:00AM - 5:00PM
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Sunday:
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The top specialties of Charles G Drake, MD, PHD include Hematology Oncology
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The office is located at 161 Fort Washington Avenue in New York, NY.
Charles G Drake, MD, PHD accepts various types of health insurance, but individual coverage may be variable. You should check with your health insurance whether the particular doctor is in network or not.
Acute Lymphocyctic Leukemia (ALL), Breast Cancer, Stomach Cancer, Hereditary Cancer Testing, Ovarian Cancer, Liver Cancer, Anemia, Cancer Prevention, Hospice, Multiple Myeloma, Chronic Lymphocytic Leukemia (CLL), Uterine Cancer, Chronic Leukemias, Colorectal Cancer, Hodgkin's Disease, Prostate Cancer, Palliative Care, DVT (Deep vein thrombosis), Eye cancer, Immunotherapy for Cancer, Chronic Myeloid Leukemia (CML), Lymphoma, Penile Cancer, Bladder Cancer, Cancer, Leukemia, Non-Hodgkin's Lymphomas, Acute Myelocytic Leukemia (AML), Lip Cancer, MUGA Scan , Glioblastoma
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